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The taxon is therefore included here in the synonymy of Smackerephedra E
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drine stimulates the release of norepinephrine, which stimulates the release of adenosine and the synthesis of prostaglandins by the activated tissue. Adenosine and prostaglandins both inhibit the effect of norepinephrine. Caffeine opposes the effect of adenosine and so increases norepinephrine release. Aspirin inhibits the synthesis of prostaglandins and so enhances the effect of norepinephrine.1
Side Effects
What users may not understand or take seriously when they seek the performance enhancing benefits of the supplement are the adverse effects it can produce.
Ephedrine raises heat production and body temperature and may increase the athlete’s risk of developing a heat injury during exercise in warm weather. In addition to increased heat production, other effects may include dizziness, headache, gastrointestinal distress, irregular heartbeat, and heart palpitations to heart attack, stroke, seizures, psychosis and even death.
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If the knowledge of these adverse effects isn’t enough to deter users, the International Olympic Committee, the National Collegiate Athletic Association (NCAA) and the National Football League (NFL) are hoping some of their recent policies banning the drug—and suspending players for doping—will be.
Research Findings
Still, are these organizations’ concerns about ephedrine really valid? In December of 2000, a study commissioned by the Food and Drug Administration (FDA) set out to answer that question by examining the adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids.
In the study, records from 140 ephedra users who experienced complications (heart attack, stroke, seizure and death) between 1997 and 1999 were reviewed. These users were young and healthy—and some had only been taking ephedrine for a few days. 2
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One-third of the patients’ complications were definitely or probably caused by ephedrine use.
Another third of the problems were possibly caused by ephedrine.
In one-fifth of the cases there was not enough information to determine the cause.
While these results illustrate the risks associated with ephedrine, the results of research illustrate its effectiveness. According to research:
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Seed cones ellipsoid, ovoid, or oblong-ovoid; bracts in 2–5 pairs or whorls, outer ones connate at base, apical pair or whorl connate for ca
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Shrubs small, to 60 cm; stems erect or ascending, grayish brown or grayish yellow, stout; green branchlets clustered at nodes, radially arranged; internodes 2–3(–4) cm × 1 5–2 mm, longitudinally furrowed, often scabridulous
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Species
The following list of species is from the Gymnosperm Database page for Ephedra.
Ephedra alata Decne
Ephedra altissima Desf.
Ephedra antisyphilitica Berl. ex C.A.Meyer - Clapweed, Erect Ephedra
Ephedra aspera Engelm. ex S.Wats. - Boundary Ephedra, Pitamoreal
Ephedra californica S.Wats. - California Ephedra, California Jointfir
Ephedra coryi E.L.Reed - Cory's Ephedra
Ephedra cutleri Peebles - Navajo Ephedra, Cutler's Ephedra, Cutler Mormon-tea, Cutler's Jointfir
Ephedra distachya L. - Joint-pine, Jointfir
Ephedra distachya subsp. helvetica (C.A.Meyer) Aschers. & Graebn.
Ephedra equisetina Bunge - Ma huang
Ephedra fasciculata A.Nels. - Arizona Ephedra, Arizona Jointfir, Desert Mormon-tea
Ephedra fedtschenkoae Pauls.
Ephedra fragilis Desf.
Ephedra fragilis subsp. campylopoda (C.A.Meyer) Aschers. & Graebn.
Ephedra frustillata Miers - Patagonian Ephedra
Ephedra funerea Coville & Morton - Death Valley Ephedra, Death Valley Jointfir
Ephedra gerardiana Wallich ex C.A.Meyer - Gerard's Jointfir, Shan Ling Ma Huang
Ephedra intermedia Schrenk ex C.A.Meyer
Ephedra lepidosperma C.Y.Cheng
Ephedra likiangensis Florin
Ephedra macedonica Kos.
Ephedra major Host
Ephedra major subsp. procera Fischer & C.A.Meyer
Ephedra minuta Florin
Ephedra monosperma C.A.Meyer
Ephedra viridis in western NevadaEphedra nevadensis S.Wats. - Nevada Ephedra, Nevada Jointfir, Nevada Mormon-tea
Ephedra pedunculata Engelm. ex S.Wats. - Vine Ephedra, Vine Jointfir
Ephedra przewalskii Stapf
Ephedra przewalskii var. kaschgarica (B.Fedtsch. & Bobr.) C.Y.Cheng
Ephedra regeliana Florin - Xi Zi Ma Huang
Ephedra saxatilis (Stapf) Royle ex Florin
Ephedra sinica Stapf - Ma Huang, Chinese ephedra
Ephedra torreyana S.Wats. - Torrey's Ephedra, Torrey's Jointfir, Torrey's Mormon-tea, Cañutillo
Ephedra trifurca Torrey ex S.Wats. - Longleaf Ephedra, Longleaf Jointfir, Longleaf Mormon-tea, Popotilla, Teposote
Ephedra viridis Coville - Green Ephedra, Green Mormon-tea
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Uses and health concerns
Ephedra distachyaThese plants have traditionally been used by indigenous people for a variety of medicinal purposes, and are a likely candidate for the Soma plant of Indo-Iranian religion. The alkaloids ephedrine and pseudoephedrine are the active constituents of the plant. Some species in the Ephedra genus have zero al
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