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drine stimulates the release of norepinephrine, which stimulates the release of adenosine and the synthesis of prostaglandins by the activated tissue.
Adenosine and prostaglandins both inhibit the effect of norepinephrine. Caffeine opposes the effect of adenosine and so increases norepinephrine release. Aspirin inhibits the synthesis of prostaglandins and so enhances the effect of norepinephrine.
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Side Effects
What users may not understand or take seriously when they seek the performance enhancing benefits of the supplement are the adverse effects it can produce. Ephedrine raises heat production and body temperature and may increase the athlete’s risk of developing a heat injury during exercise in warm weather. In addition to increased heat production, other effects may include dizziness, headache, gastrointestinal distress, irregular heartbeat, and heart palpitations to heart attack, stroke, seizures, psychosis and even death.
These side effects can vary among individuals and occasions and don't always depend on how much is consumed. Also, combining caffeine (from coffee, Guarana, mate, or any other source) with ephedrine-containing products (such as those mentioned earlier) greatly increases the risks.2,3
If the knowledge of these adverse
ephedra side effects effects isn’t enough to deter users, the International Olympic Committee, the National Collegiate Athletic Association (NCAA) and the National Football League (NFL) are hoping some of their recent policies banning the drug—and suspending players for doping—will be.
Research Findings
Still, are these organizations’ concerns about ephedrine really valid? In December of 2000, a study commissioned by the Food and
Zone Diet Drug Administration (FDA) set out to answer that question by examining the adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids.
In the study, records from 140 ephedra users who experienced complications (heart attack, stroke, seizure and death) between 1997 and 1999 were reviewed.
These users were young and healthy—and some had only been taking ephedrine for a few days. 2
The researchers found that:
One-third of the patients’ complications were definitely or probably caused by ephedrine use.
Another third of the problems were possibly caused by ephedrine.
In one-fifth of the cases there was not enough information to determine the cause.
While these results illustrate the risks associated with ephedrine, the results of research illustrate its effectiveness. According to research:
A combination of ephedrine and caffeine (0.8 to 1.0 mg of ephedrine per kg and 4 to 5 mg of caffeine per kg consumed 1½ hours before exercise) may improve both anaerobic and high-intensity aerobic performance.4,5
Combining ephedrine and caffeine (20 mg ephedrine and 200 mg caffeine, consumed three times per day) with a low calorie diet (1,000 calories) may also help to promote weight loss in obese individuals. 6,7
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Over 5000 years ago ephedra (under the name Ma huang) has been used in Chinese medicine to treat several disorders. Amongst others asthma and bronchitis were to be treated properly with ephedra. Ephedra comes from a plant that has a few powerful active compounds, of which ephedrine is the most useful. More information on the chemical connections en the extraction of the active substances is to be read in chemistry.
Over the last few years ephedra has gained much more attention for its side-effects: an increased metabolism, plus the thermeogenic and fat burning qualities that come along with that. This gives the body stimulation and provides energy. Thanks to these qualities ephedra now has a status of weight-loss supplement, smartdrug and sports supplement. A status that has recently become controversial because of the ban on ephedra products in the United States and the Netherlands.
Read about the why, when and how in legal?.
The menu parts all contain articles, which were placed in the original English version. Besides we have some users experiences, a users guide, Frequently Asked Questions, links and a forum.
* News *
October 3 , 2005 - Ephedra-free diet pills not risk-free
In a scramble to develop new replacement weight-loss aids, drug manufacturers produced drugs containing extracts of bitter orange. This supplement has been used in traditional Chinese medicine for digestive problems.
Studies are finding these new ephedra-free diet pills carry some side effects that are similar to ephedra products.
This botanical contains a compound similar to ephedra, called synephrine. Both of these compounds stimulate the central nervous system and are thought to increase the metabolism. Also both raise blood pressure and heart rate, according to research on Advantra Z and Xenadrine EFX at the University of California, San Francisco.
Dr. Christine Haller, lead author of the University of California, San Francisco study, points out that little research has been done to determine whether or not these new ephedra-free diet pills are safe or effective. She says the main concern about these new diet pills is the risk they pose to people with elevated blood pressure and conditions like diabetes: two medical conditions which are common in overweight and obese individuals.
“This does indicate that people should use caution when using these ephedra-free diet drugs]” Haller says.
In 1927, the U.S. medical community began to use ephedrine, which is the
active ingredient in ma haung, to open bronchial passages in patients with
asthma. As the supplies of
Ephedra vulgaris
began to dwindle, pharmaceutical
companies began to search for a synthetic alternative. Amphetamine was first
synthesized in 1887, but because there was very little interest in it, the substance
went unnoticed until it became the alternative to ephedrine (Feldman
et al., 1997). By the 1930s, all the major effects of amphetamine were known.
While researOver 5000 years ago ephedra (under the name Ma huang) has been used in Chinese medicine to treat several disorders. Amongst others asthma and bronchitis were to be treated properly with ephedra. Ephedra comes from a plant that has a few powerful active compounds, of which ephedrine is the most useful.
More information on the chemical connections en the extraction of the active substances is to be read in chemistry.
Over the last few years ephedra has gained much more attention for its side-effects: an increased metabolism, plus the thermeogenic and fat burning qualities that come along with that. This gives the body stimulation and provides energy. Thanks to these qualities ephedra now has a status of weight-loss supplement, smartdrug and sports supplement. A status that has recently become controversial because of the ban on ephedra products in the United States and the Netherlands. Read about the why, when and how in legal?.
The menu parts all contain articles, which were placed in the original English version. Besides we have some users experiences, a users guide, Frequently Asked Questions, links and a forum.
* News *
October 3 , 2005 - Ephedra-free diet pills not risk-free
In a scramble to develop new replacement weight-loss aids, drug manufacturers produced drugs containing extracts of bitter orange. This supplement has been used in traditional Chinese medicine for digestive problems. Studies are finding these new ephedra-free diet pills carry some side effects that are similar to ephedra products.
This botanical contains a compound similar to ephedra, called synephrine. Both of these compounds stimulate the central nervous system and are thought to increase the metabolism. Also both raise blood pressure and heart rate, according to research on Advantra Z and Xenadrine EFX at the University of California, San Francisco.
Dr. Christine Haller, lead author of the University of California, San Francisco study, points out that little research has been done to determine whether or not these new ephedra-free diet pills are safe or effective. She says the main concern about these new diet pills is the risk they pose to people with elevated blood pressure and conditions like diabetes: two medical conditions which are common in overweight and obese individuals.
“This does indicate that people should use caution when using these ephedra-free diet drugs]” Haller says.
In 1927, the U.S. medical community began to use ephedrine, which is the
active ingredient in ma haung, to open bronchial passages in patients with
asthma.
As the supplies of
Ephedra vulgaris
began to dwindle, pharmaceutical
companies began to search for a synthetic alternative. Amphetamine was first
synthesized in 1887, but because there was very little interest in it, the substance
went unnoticed until it became the alternative to ephedrine (Feldman
et al., 1997). By the 1930s, all the major effects of amphetamine were known.
While researOver 5000 years ago ephedra (under the name Ma huang) has been used in Chinese medicine to treat several disorders. Amongst others asthma and bronchitis were to be treated properly with ephedra. Ephedra comes from a plant that has a few powerful active compounds, of which ephedrine is the most useful. More information on the chemical connections en the extraction of the active substances is to be read in chemistry.
Over the last few years ephedra has gained much more attention for its side-effects: an increased metabolism, plus the thermeogenic and fat burning qualities that come along with that. This gives the body stimulation and provides energy. Thanks to these qualities ephedra now has a status of weight-loss supplement, smartdrug and sports supplement. A status that has recently become controversial because of the ban on ephedra products in the United States and the Netherlands. Read about the why, when and how in legal?.
The menu parts all contain articles, which were placed in the original English version.
Besides we have some users experiences, a users guide, Frequently Asked Questions, links and a forum.
* News *
October 3 , 2005 - Ephedra-free diet pills not risk-free
In a scramble to develop new replacement weight-loss aids, drug manufacturers produced drugs containing extracts of bitter orange. This supplement has been used in traditional Chinese medicine for digestive problems. Studies are finding these new ephedra-free diet pills carry some side effects that are similar to ephedra products.
This botanical contains a compound similar to ephedra, called synephrine. Both of these compounds stimulate the central nervous system and are thought to increase the metabolism.
Also both raise blood pressure and heart rate, according to research on Advantra Z and Xenadrine EFX at the University of California, San Francisco.
Dr. Christine Smackerephedra Haller, lead author of the University of California, San Francisco study, points out that little research has been done to determine whether or not these new ephedra-free diet pills are safe or effective. She says the main concern about these new diet pills is the risk they pose to people with elevated blood pressure and conditions like diabetes: two medical conditions which are common in overweight and obese individuals.
“This does indicate that people should use caution when using these ephedra-free diet drugs” Haller says.
In 1927, the U.S. medical community began to use ephedrine, which is the
active ingredient in ma haung, to open bronchial passages in patients with
asthma. As the supplies of
Ephedra vulgaris
began to dwindle, pharmaceutical
companies began to search for a synthetic alternative. Amphetamine was first
synthesized in 1887, but because there was very little interest in it, the substance
went unnoticed until it became the alternative to ephedrine (Feldman
et al., 1997).
By the 1930s, all the major effects of amphetamine were known.
While researOver 5000 years ago ephedra (under the name Ma huang) has been used in Chinese medicine to treat several disorders. Amongst others asthma and bronchitis were to be treated properly with ephedra.
Ephedra comes from a plant that has a few powerful active compounds, of which ephedrine is the most useful.
More information on the chemical connections en the extraction Diets of the active substances is to be read in chemistry.
Over the last few years ephedra has gained much more attention for its side-effects: an increased metabolism, plus the thermeogenic and fat burning qualities that come along with that. This gives the body stimulation and provides energy. Thanks to these qualities ephedra now has a status of weight-loss supplement, smartdrug and sports supplement. A status that has recently become controversial because of the ban on ephedra products in the United States and the Netherlands. Read about the why, when and how in legal?.
The menu parts all contain articles, which were placed in the original English version. Besides we have some users experiences, a users guide, Frequently Asked Questions, links and a forum.
* News *
October 3 , 2005 - Ephedra-free diet pills not risk-free
In a scramble to develop new replacement weight-loss aids, drug manufacturers produced drugs containing extracts of bitter orange. This supplement has been used in traditional Chinese medicine for digestive problems.
Studies are finding these new ephedra-free diet pills carry some side effects that are similar to ephedra products.
This botanical contains a compound similar to ephedra, called synephrine. Both of these compounds stimulate the central nervous system and are thought to increase the metabolism. Also both raise blood pressure and heart rate, according to research on Advantra Z and Xenadrine EFX at the University of California, San Francisco.
Dr. Christine Haller, lead author of the University of California, San Francisco study, points out that little research has been done to determine whether or not these new ephedra-free diet pills are safe or effective. She says the main concern about these new diet pills is the risk they pose to people with elevated blood pressure and conditions like diabetes: two medical conditions which are common in overweight and obese individuals.
“This does indicate that people should use caution when using these ephedra-free diet drugs” Haller says.
In 1927, the U.S. medical community began to use ephedrine, which is the
active ingredient in ma haung, to open bronchial passages
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asthma. As the supplies of
Ephedra vulgaris
began to dwindle, pharmaceutical
companies began to search for a synthetic alternative.
Amphetamine was first
synthesized in 1887, but because there was very little interest in it, the substance
went unnoticed until it became the alternative to ephedrine (Feldman
et al., 1997). By the 1930s, all the major effects of amphetamine were known.
While resear
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